Sharath S Hegde Selected Research

darifenacin

1/2008	Pharmacological analysis of the interaction of antimuscarinic drugs at M(2) and M(3) muscarinic receptors in vivo using the pithed rat assay.
11/2006	Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites?
2/2006	Muscarinic receptors in the bladder: from basic research to therapeutics.

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Sharath S Hegde Research Topics

Disease

6	Infections 12/2014 - 08/2004
5	Chronic Obstructive Pulmonary Disease (COPD) 12/2020 - 10/2012
4	Overactive Urinary Bladder (Overactive Bladder) 03/2009 - 01/2004
2	Angioedema 01/2019 - 04/2011
2	Body Weight (Weight, Body) 03/2012 - 08/2004
2	Bradycardia 03/2010 - 01/2008
2	Constipation 03/2009 - 02/2006
2	Pneumonia (Pneumonitis) 01/2008 - 10/2005
1	Hypertension (High Blood Pressure) 01/2019
1	Bacterial Pneumonia 12/2014
1	Opioid-Induced Constipation 06/2013
1	Diarrhea 06/2013
1	Hypothermia 06/2013
1	Glaucoma 02/2013
1	Sleepiness 03/2009
1	Mydriasis 03/2009

Drug/Important Bio-Agent (IBA)

7	telavancin FDA Link 12/2014 - 08/2004
5	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 10/2012 - 02/2006
4	Muscarinic AntagonistsIBA 03/2015 - 01/2004
4	Vancomycin FDA LinkGeneric 04/2010 - 10/2005
3	LipoglycopeptidesIBA 12/2014 - 10/2005
3	darifenacin FDA Link 01/2008 - 02/2006
3	oxybutynin (Tavor)FDA LinkGeneric 01/2008 - 02/2006
2	revefenacinIBA 12/2020 - 01/2018
2	SolutionsIBA 12/2020 - 01/2018
2	Antihypertensive Agents (Antihypertensives)IBA 01/2019 - 04/2011
2	Type 1 Angiotensin ReceptorIBA 01/2019 - 04/2011
2	omapatrilatIBA 01/2019 - 04/2011
2	Neprilysin (Neutral Endopeptidase)IBA 01/2019 - 04/2011
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2019 - 04/2011
2	BradykininIBA 01/2019 - 04/2011
2	Bronchodilator Agents (Bronchodilators)IBA 01/2018 - 10/2014
2	Methacholine Chloride (Methacholine)FDA Link 03/2010 - 01/2008
2	Tolterodine Tartrate (Detrol)FDA Link 01/2008 - 11/2006
2	Solifenacin Succinate FDA Link 01/2008 - 11/2006
1	Cholinergic Antagonists (Anticholinergics)IBA 12/2020
1	ReninIBA 01/2019
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2019
1	EnzymesIBA 01/2019
1	Cholinergic ReceptorsIBA 01/2018
1	Cholinergic Agents (Cholinergics)IBA 01/2018
1	batefenterolIBA 03/2015
1	diphenyl (biphenyl)IBA 03/2015
1	Salmeterol Xinafoate (Serevent)FDA Link 03/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2014
1	Castor Oil (Oil, Castor)IBA 06/2013
1	Loperamide (Imodium)FDA LinkGeneric 06/2013
1	Morphine (MS Contin)FDA LinkGeneric 06/2013
1	Naltrexone (ReVia)FDA LinkGeneric 06/2013
1	Narcotic Antagonists (Opioid Antagonists)IBA 06/2013
1	ADL 08-0011IBA 06/2013
1	3- (8- (2- (cyclohexylmethyl(2,3- dihydroxypropionyl)amino)ethyl)- 8- azabicyclo(3.2.1)oct- 3- yl)benzamideIBA 06/2013
1	alvimopan FDA Link 06/2013
1	Carbonic Anhydrase IIIBA 02/2013
1	ProstaglandinsIBA 02/2013
1	cefilavancinIBA 03/2012
1	Valsartan (Vals)FDA Link 04/2011
1	candoxatrilIBA 04/2011
1	Muscarinic AgonistsIBA 03/2010
1	1- (4- methoxypyridin- 3- ylmethyl)- 4- ((N- (7- (3- (S)- 1- carbamoyl- 1,1- diphenylmethyl)pyrrolidin- 1- yl)hept- 1- yl)- N- (isopropyl)amino)piperidineIBA 03/2009
1	Methicillin (Metin)FDA Link 01/2008
1	Tiotropium Bromide (Spiriva)FDA Link 01/2008
1	propiverineIBA 11/2006
1	Linezolid (Zyvox)FDA Link 10/2005

Therapy/Procedure

1	Mechanical Ventilators (Ventilator) 12/2014
1	Oral Administration 06/2013
1	Therapeutics 01/2004